This is the sample connection string in the web.config file
Before Encrypt
<configuration>
  <connectionStrings>
    <add name="SqlServices" connectionString="Data Source=localhost;Integrated Security=SSPI;Initial Catalog=Northwind;" />
  </connectionStrings>
</configuration>
Encrypting web.config file
1. Open Command Prompt with Administrator mode
2. Move the directory to following:
cd C:\Windows\Microsoft.NET\Framework\v4.0.30319
3. Type following command with your web.config file location.
Example: If your web.config file is located as D:\MyProject\web.config, type following command to encrypt.
ASPNET_REGIIS -pef "connectionStrings" "D:\MyProject\"
Note: The parameter “connectionStrings” is case sensitive.
Web.config file after encryption:
<configuration>
  <connectionStrings configProtectionProvider="RsaProtectedConfigurationProvider">
    <EncryptedData Type="http://www.w3.org/2001/04/xmlenc#Element"
      xmlns="http://www.w3.org/2001/04/xmlenc#">
      <EncryptionMethod Algorithm="http://www.w3.org/2001/04/xmlenc#tripledes-cbc" />
      <KeyInfo xmlns="http://www.w3.org/2000/09/xmldsig#">
        <EncryptedKey xmlns="http://www.w3.org/2001/04/xmlenc#">
          <EncryptionMethod Algorithm="http://www.w3.org/2001/04/xmlenc#rsa-1_5" />
          <KeyInfo xmlns="http://www.w3.org/2000/09/xmldsig#">
            <KeyName>Rsa Key</KeyName>
          </KeyInfo>
          <CipherData>
            <CipherValue>ZbDTF00MYzUUW5U3w3PU0rfiAH1UKhvuLSNWPmB/YifBKne6HAWfVc3CnKVimyP8SFyamaR5oAIAxj/xavfpox8EOYXNI+afsksiuA5huSDupCZKNuXq+VCZrdIyn6YOq+W7s3Ojlu7q9VwKcoKurl28l2hcPvWkBk11KYB7hr0=</CipherValue>
          </CipherData>
        </EncryptedKey>
      </KeyInfo>
      <CipherData>
        <CipherValue>42IPPRUjJxCNDHEBLCAJI4/NyLpLueZSBzUXO69lVdZU8+nLpxO+opnbZNxqddyzNnbCO1Uk2Da3ljExkqnLIxT2zs90JAhZvJ5ljIgCipq7ZEp7zHOpvTH9fBGoZJJWhgdddOrHZsLDE9mILjlvBHDhPQrYcMHtY6oLIbxJq92it82iBJv0fS7v1S/o0p4hAtfky+6hXCZWSKUJHr88NDrKe2EEK3mazD2QD5Ozf/w=</CipherValue>
      </CipherData>
    </EncryptedData>
  </connectionStrings>
</configuration>
Decrypting the Connection String
ASPNET_REGIIS -pdf "connectionStrings" "D:\MyProject\"
-pdf: Decrypting
-pef: Encrypting